SPECIAL FOCUS: Early-onset colorectal cancer
نویسندگان
چکیده
منابع مشابه
BIRC5 Genomic Copy Number Variation in Early-Onset Breast Cancer
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IMPORTANCE Li-Fraumeni syndrome, usually characterized by germline TP53 mutations, is associated with markedly elevated lifetime risks of multiple cancers, and has been linked to an increased risk of early-onset colorectal cancer. OBJECTIVE To examine the frequency of germline TP53 alterations in patients with early-onset colorectal cancer. DESIGN, SETTING, AND PARTICIPANTS This was a multi...
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ژورنال
عنوان ژورنال: Colorectal Cancer
سال: 2020
ISSN: 1758-194X,1758-1958
DOI: 10.2217/crc-2020-0030